According to David Clem, managing director of Lyme Properties, all 1,313,000 sf of the site has been committed. Lyme Properties is developer and manager of the project with Scottish Widows, a UK insurer, its equity partner.

In addition to its headquarters, Genzyme will lease 150,000 sf in a nearby laboratory building. Vertex Pharmaceuticals has signed a letter of intent for 250,000 sf lab space in a third biotech building. Atlanta-based Hardin Capital plans to develop a 300-room hotel and 160 condominiums while Constellation Productions, a nonprofit organization, will develop the four theaters. Lyme will build additional residential, retail and office space.

Kendall Square is under construction on land formerly owned by Commonwealth Energy, which has been classified as a brownfields site by the Massachusetts Department of Environmental Protection. According to the developer, environmental cleanup is underway at the site.

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