Opening at 1 p.m. Jan. 10, the 250-room Renaissance Portsmouth Hotel and the 24,000-sf Waterfront Conference Center is located directly on the water at 425 Water St. A restaurant with waterfront dining, an indoor pool, and an executive learning center and case study amphitheater built to International Association of Conference Centers standards are among the center's amenities. Crestline Capital's management subsidiary, is managing both the hotel and conference center through a long-term management contract.

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