The project includes improvements and new construction across the hospital's 27.7-acre campus. In response to community input, the site plan incorporates new residential construction including townhouses, homes and apartments as well as medical and commercial office space, retail development and green space.

A renovation of the existing hospital building will preserve its historic clock tower and add a 140-space covered garage. To be called St Luke's Place, the 137-year-old former hospital will be redeveloped as a 140-unit condominium complex and will include retail space and a garage. Additional residential development connected to the project will consist of up to 100 newly constructed townhouses and single-family homes.

The Saint Luke's Campus Plan's initial office component comprises a 52,000-sf building at Shaker Boulevard and East 116th Street that will house an urgent-care center, dental clinic, pharmacy and medical offices. Occupancy is tentatively scheduled for third quarter 2003. Development of a second, similarly sized office building is also under consideration.