The news became public after GSK filed papers with the NJ Department of Labor indicating that it would ax more than 100 staffers within the next 60 days, mostly in marketing, compliance, payroll and business analysis. Some 50 staffers will remain on-site temporarily as the local operations gradually shut down. A GSK spokesman could not be reached for comment.

The four-story asset at 110 Allen Rd., also known as Bernards 78 for its proximity to I-78, totals nearly 202,000 sf. The building is owned by a local partnership advised by Lend Lease Real Estate Investments, and a full-floor block of direct space is currently listed with an asking price of $29.75 per sf.

Formed in 1999 by former big pharma execs, Reliant had grown into one of the world's largest privately owned pharmaceutical companies prior to its acquisition by GSK. Focusing on cardiovascular products and services, the company initially moved into Bernards 78 in early 2001, filling the building with its lease of 52,417 sf. As additional space opened up, Reliant expanded multiple times to its current 96,000 sf, most recently with a 20,000-sf addition a couple of years ago.