The second gift--$110 million--will be used to redesign Tisch Hospital, NYU's renowned flagship hospital, built in 1963. It comes from a longstanding family of NYU benefactors who wishes to remain anonymous, according to a release from NYU Langone.

Helen and Martin Kimmel, both trustees of the medical center, earlier established research centers for stem cell biology and for biology and medicine, endowed two basic science professorships and supported a wide range of specific research programs, according to a release. NYU expects to break ground on the new Helen L. and Martin S. Kimmel Pavilion in about four years and to have it fully up and running in seven years.

This year, NYU Langone launched its new name and brand identity, following a $100-million donation from Home Depot co-founder Ken Langone and his wife Elaine. The hospital expanded its network of physicians as it opened new ambulatory care facilities at Downtown and in Westchester County, as well as a large multi-specialty center in Queens. New affiliations, ranging from Woodhull Hospital to Clinico Modelo in northern Manhattan, have contributed to making NYU the largest academic affiliate of New York City's Health and Hospitals Corp., the release states.