NUTLEY, NJ–Roche, the Swiss pharmaceutical company, announced Tuesday that it will shutter its research center in Nutley at the end of next year, after 80 years of operation in the North Jersey suburb. This means the loss of 1,000 jobs – and, commercial real estate experts said, a huge new hole blown into the market.

Roche announced it will build a smaller facility employing 240 people somewhere on the East Coast to handle late-stage R & D, but said it has not yet identified a site. Roche plans to sell the Nutley property by 2015, and consolidate most R&D activities in its offices in Switzerland and Germany.

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