SAN DIEGO—BioMed Realty Trust is in the midst of a realignment that will include a number of promotions and additions to its leadership team.

The company announced Wednesday that, effective immediately, president and COO Kent Griffin is leaving BioMed to pursue other business opportunities.  During his nine-year career with firm, Griffin served as chief financial officer before taking on his most recent position. As a result of Griffin’s departure, the company expects to record a severance charge of $0.05 per diluted share in the first quarter of 2015.

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