Krish S. Krishnan, chairman and chief executive officer, left, and Suma Krishnan, founder and chief operating officer of Krystal Biotech, Pittsburgh, PA
PITTSBURGH, PA—Krystal Biotech, a gene therapy company developing treatments for rare dermatological diseases, has completed construction of Ancoris, a new state-of-the-art Good Manufacturing Practice facility near the company's headquarters in Pittsburgh.
The new facility will support clinical and commercial manufacturing of Krystal's lead product candidate, KB103, for the treatment of dystrophic epidermolysis bullosa, a genetic skin disorder that causes skin to tear or blister from minor contact. The facility will be officially open in 1Q 2019 following completion of the first engineering run.
“Our development of internal manufacturing capabilities bolsters our position for commercial readiness as we execute on our vision to bring our therapies to the patient communities in —need,” says Krish S. Krishnan, chairman and chief executive officer of Krystal Biotech. “We thank the City of Pittsburgh and the Mayor's office for helping us complete construction in a timely manner and we intend to have a formal inauguration following completion of a trial run in 1Q 2019.”
The 4,500 square foot facility has been designed to satisfy the necessary manufacturing requirements for commercial development of KB103. A second phase of the manufacturing strategy has begun with plans to build a second, larger GMP manufacturing facility in Pittsburgh that will support the anticipated commercial demand for future developmental pipeline programs. The second facility is anticipated to be complete in 2020.
“Having our own GMP facility will allow us to keep important proprietary process development and associated intellectual property in-house,” says Suma Krishnan, founder and chief operating officer of Krystal. “Ancoris and the second GMP facility we have planned will ensure that we are able to meet the manufacturing demands of all our research and potential commercial programs.”
|Want to continue reading?
Become a Free ALM Digital Reader.
Once you are an ALM Digital Member, you’ll receive:
- Breaking commercial real estate news and analysis, on-site and via our newsletters and custom alerts
- Educational webcasts, white papers, and ebooks from industry thought leaders
- Critical coverage of the property casualty insurance and financial advisory markets on our other ALM sites, PropertyCasualty360 and ThinkAdvisor
Already have an account? Sign In Now
*May exclude premium content© 2024 ALM Global, LLC, All Rights Reserved. Request academic re-use from www.copyright.com. All other uses, submit a request to [email protected]. For more information visit Asset & Logo Licensing.
Steve Lubetkin
Steve Lubetkin is the New Jersey and Philadelphia editor for GlobeSt.com. He is currently filling in covering Chicago and Midwest markets until a new permanent editor is named. He previously filled in covering Atlanta. Steve’s journalism background includes print and broadcast reporting for NJ news organizations. His audio and video work for GlobeSt.com has been honored by the Garden State Journalists Association, and he has also been recognized for video by the New Jersey Chapter of the Society of Professional Journalists. He has produced audio podcasts on CRE topics for the NAR Commercial Division and the CCIM Institute. Steve has also served (from August 2017 to March 2018) as national broadcast news correspondent for CEOReport.com, a news website focused on practical advice for senior executives in small- and medium-sized companies. Steve also reports on-camera and covers conferences for NJSpotlight.com, a public policy news coverage website focused on New Jersey government and industry; and for clients of StateBroadcastNews.com, a division of The Lubetkin Media Companies LLC. Steve has been the computer columnist for the Jewish Community Voice of Southern New Jersey, since 1996. Steve is co-author, with Toronto-based podcasting pioneer Donna Papacosta, of the book, The Business of Podcasting: How to Take Your Podcasting Passion from the Personal to the Professional. You can email Steve at [email protected].
