Edward J. Minskoff Equities is marketing a stake in a Lower Manhattan office building that has established itself as a magnet for life science players.

The 23-story building at 101 Avenue of the Americas in the Hudson Square neighborhood is 93% occupied, with 40% of the current leases occupied by life-science tenants.

Minskoff owns the tower via a leasehold interest and is talking to investors about selling a partial interest, according to a Green Street alert. The size of the stake is negotiable, but Minskoff is seeking to attract bids that would value the entire building at more than $250M, or $584 per SF.

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