Landlords of Bay Area life science campuses afflicted with high vacancy rates in an oversupplied market are hoping a bright green shoot on the San Francisco Peninsula is the harbinger of a long-awaited rebound in 2025.

Biotech startup Vaxcyte has inked a 10-year deal to more than double the footprint of its headquarters at the Alexandria Center for Life Science in San Carlos. The new lease expands Vaxcyte’s HQ to almost 259K SF from the 113K SF space it has occupied at 825 Industrial Road.

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