LA JOLLA, CA-The biotech firm, which specializes in the treatment of metabolic diseases, has signed a long-term lease at Torrey Pines Research Center. The lease calls for Metabasis to take 81,800 sf.

SAN DIEGO-The 130,805-sf office project receives a refinance to stabilize the asset. The property changed hands last October on a $22-million sale.

SORRENTO MESA, CA-The Los Angeles-based real estate firm will develop a three-story medical center. The project is another sign of a strengthening market in the San Diego office arena.

CARLSBAD, CA-The Illinois-based real estate group opens a Southern California office and taps industry vet Stephen Hess to oversee the local operations.

SAN DIEGO-The 15-story office project fills prelease space to Comerica Bank and Cox Communications. Both Comerica and Cox will take two floors in the 306,700-sf office tower.

CARLSBAD, CA-Integrated Capital Technologies takes the class B office space in the metro area. The property is a two-story, multi-tenant office building counting 83,029 sf.

CARLSBAD, CA-Integrated Capital Technologies takes the class B office space in the metro area. The property is a two-story, multi-tenant office building counting 83,029 sf.

SAN DIEGO-The real estate investment advisor takes Pacific Technology Park, a 440,569-sf mixed-use campus. The property counts four buildings and is a mix of industrial, flex and office space.